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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 254 | Human, Mouse |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | ABCA1 Rabbit Polyclonal Antibody detects endogenous levels of ABCA1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
ABCA1 also known as ABC1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABCA1 plays a crucial role in lipid metabolism by facilitating the efflux of cholesterol and phospholipids from cells, which is vital for maintaining cellular homeostasis and preventing the accumulation of lipids that can lead to atherosclerosis. ABCA1 protein is predominantly located in the plasma membrane of various cell types, including macrophages, where ABCA1 is essential for the formation of high-density lipoprotein (HDL) and the regulation of cholesterol levels in the body. Mutations in the ABCA1 gene are associated with Tangier disease, a condition characterized by severely low levels of HDL cholesterol, underscoring the importance of ABCA1 in cardiovascular health. |
| Product Image Gallery | |
 Western blot analysis of extracts on MCF7, Mouse liver cells, using ABCA1 Rabbit Polyclonal Antibody (EAB13645) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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