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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 28 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Amphiregulin/AREG Rabbit Polyclonal Antibody detects endogenous levels of Amphiregulin/AREG protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Amphiregulin also known as SDGF, AREG, CRDGF is a member of the epidermal growth factor family. Amphiregulin plays a crucial role in cellular signaling and is primarily produced by keratinocytes, where Amphiregulin functions as an autocrine growth factor. Amphiregulin is vital for normal human keratinocyte proliferation and binds to the ErbB-1 receptor, which is essential for the development of epithelial tissues in the skin, lungs, and gastrointestinal tract. Research has shown that withdrawal of Amphiregulin leads to downregulation of telomerase activity in human keratinocytes, indicating Amphiregulin′s role in regulating cellular aging processes. |
| Product Image Gallery | |
 Western blot analysis of extracts on HBE cells, using Amphiregulin/AREG Rabbit Polyclonal Antibody (EAB13658) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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