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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | IHC-P, IF, ELISA | 31 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| IHC-P=1:50-300 IF=1:50-300 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | IL-1α Rabbit Polyclonal Antibody detects endogenous levels of IL-1α protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
IL-1α also known as IL-1alpha, IL1A is a member of the interleukin 1 cytokine family. IL-1α plays a vital role in the immune response and inflammation. IL-1α is primarily produced by activated macrophages and is crucial for mediating the body′s response to infection and injury. IL-1α is predominantly located in the cytoplasm of cells, where IL-1α is synthesized and stored in an inactive form. Upon cellular activation, IL-1α is released into the extracellular space, where IL-1α can bind to the IL-1 receptor and initiate a cascade of inflammatory responses. This localization allows for rapid release and action during immune challenges, making IL-1α a critical player in the regulation of immune responses, including the activation of T and B lymphocytes and natural killer cells. |
| Product Image Gallery | |
 Immunohistochemistry analysis of paraffin-embedded Human lung carcinoma tissue, using IL-1α Rabbit Polyclonal Antibody (EAB13660) at 1:100 dilution.
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