Angiopoietin-2/Ang-2 Rabbit Monoclonal Antibody
Catalog #:EAB21792
Host / Isotype Clonality Applications MW (kDa) Reactivity
Rabbit IgG Monoclonal WB, IHC-P, IF/ICC 55 Human, Mouse, Rat
Applications Dilutions
The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user.
WB=1:1000-5000 
IHC-P=1:100-500 
IF/ICC=1:100-500
Application Key

WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry

Reactivity Key

H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Information
Conjugate Unconjugate
Specificity Angiopoietin-2/Ang-2 Rabbit Monoclonal Antibody detects endogenous levels of Angiopoietin-2/Ang-2 protein.
Purification Affinity purification
Concentration 1mg/ml
Format Liquid
Formulation In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping Gel Pack
Storage Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
UniProt ID

O15123

Entrez Gene ID

285

Product Description

Angiopoietin-2 also known as Ang-2, ANGPT2 is a member of the angiopoietin family of growth factors. Angiopoietin-2 plays a critical role in regulating angiogenesis and vascular remodeling, acting as a natural antagonist to angiopoietin-1, which is essential for endothelial cell development and stabilization. Angiopoietin-2 expression is particularly significant in adult tissues undergoing vascular remodeling, where Angiopoietin-2 can promote inflammation and contribute to pathological conditions such as cancer and cardiovascular diseases. The interaction between Angiopoietin-2 and Tie-2 receptor is crucial for modulating vascular permeability and endothelial cell survival, making Angiopoietin-2 a key player in both normal physiological processes and various disease states.

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For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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