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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF, ELISA | 45 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 IF=1:50-300 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | ANGPTL4 Rabbit Polyclonal Antibody detects endogenous levels of ANGPTL4 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
ANGPTL4 also known as HFARP is a secreted protein that plays a crucial role in maintaining endothelial cell integrity and function, particularly under conditions of hypoxia. ANGPTL4 is induced in endothelial cells during hypoxic stress, highlighting ANGPTL4′s importance in vascular biology and response to oxygen deprivation. Structurally, ANGPTL4 features a hydrophobic N-terminal region characteristic of a secretory signal sequence, along with a consensus glycosylation site that may influence stability and activity. Notably, ANGPTL4 serves as a potential biomarker for renal cell carcinoma, as ANGPTL4 is uniquely expressed in these tumor cells, providing insights into tumor biology and potential therapeutic targets. Additionally, Angptl4 regulates glucose homeostasis, lipid metabolism, and insulin sensitivity, making ANGPTL4 a significant factor in metabolic disorders such as diabetes. |
| Product Image Gallery | |
 Western blot analysis of extracts on MCF7, Raw264.7 cells, using ANGPTL4 Rabbit Polyclonal Antibody (EAB13663) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
 Immunohistochemical analysis of paraffin-embedded Human testis tissue, using ANGPTL4 Rabbit Polyclonal Antibody (EAB13663) at 1:100 dilution.
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