| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF, ELISA | 35 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-300 IF=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | AQP4 Rabbit Polyclonal Antibody detects endogenous levels of AQP4 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
AQP4(Aquaporin 4) is a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. AQP4 plays a crucial role in regulating water homeostasis in the body, particularly in the central nervous system and skeletal muscle. AQP4 is predominantly localized to the sarcolemma of fast-twitch muscle fibers, where AQP4 facilitates rapid water transport, essential for muscle contraction and recovery. AQP4 presence in the brain is vital for maintaining water balance in the extracellular space, which is critical for neuronal function and overall brain health. AQP4 dysregulation has been implicated in various neurological disorders, making AQP4 a significant target for research in understanding and treating conditions such as edema and multiple sclerosis. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, 293T cells, using AQP4 Rabbit Polyclonal Antibody (EAB11646) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
 Immunohistochemical analysis of paraffin-embedded Human lung carcinoma tissue, using AQP4 Rabbit Polyclonal Antibody (EAB11646) at 1:100 dilution.
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