ATOH1/MATH-1 Rabbit Polyclonal Antibody
Catalog #:EAB13681
Host / Isotype Clonality Applications MW (kDa) Reactivity
Rabbit IgG Polyclonal WB, ELISA 38 Human, Mouse
Application Key

WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry

Reactivity Key

H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Applications Dilutions
The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user.
WB(Westem Blotting)
IHC-P(Immunohistochemistry-Paraffin)
IF/ICC(Immunofluorescence/Immunocytochemistry)
ELISA(Enzyme-linked Immunosorbent Assay)
WB=1:500-2000
Product Information
Conjugate Unconjugate
Specificity ATOH1/MATH-1 Rabbit Polyclonal Antibody detects endogenous levels of ATOH1/MATH-1 protein.
Purification Affinity purification
Concentration 1mg/ml
Format Liquid
Formulation In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping Gel Pack
Storage Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
UniProt ID

Q92858

Entrez Gene ID

474

Product Description

MATH-1 also known as Ath1, HATH-1, ATOH1 is a 351 amino acid helix-loop-helix transcription factor that plays a crucial role in the development of the nervous system. MATH-1 helps researchers study neural progenitor cell differentiation, where MATH-1 activates E box-dependent transcription, influencing various neural cell types. MATH-1 expression begins in cranial ganglions and the dorsal part of the central nervous system by embryonic day 9.5 in mice, becomes restricted to the external granular layer of the cerebellum by day 18, and remains undetectable in the adult nervous system. Proper MATH-1 regulation is essential for neural development, as dysregulation can lead to neurodevelopmental disorders.

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For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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