| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF, ELISA | 49 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-300 IF=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | BMP7 Rabbit Polyclonal Antibody detects endogenous levels of BMP7 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
BMP7 also known as OP-1 is a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. BMP7 plays a crucial role in cartilage and bone formation, making BMPs essential for skeletal development and repair. BMP7 promotes osteogenesis and chondrogenesis, while BMP7 signaling pathways maintain bone homeostasis. BMP7 is primarily located in the extracellular matrix and secreted by various cell types, including osteoblasts and chondrocytes, underscoring BMP7′s importance in bone and cartilage development regulation. BMP7 has been implicated in healing processes following injury, and BMP7 dysregulation can lead to various skeletal disorders. |
| Product Image Gallery | |
 Western blot analysis of extracts on Jurkat, Rat muscle cells, using BMP7 Rabbit Polyclonal Antibody (EAB13701) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
 Immunohistochemical analysis of paraffin-embedded Human tonsil tissue, using BMP7 Rabbit Polyclonal Antibody (EAB13701) at 1:100 dilution.
|
