| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF/ICC, ELISA | 56 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-300 IF/ICC=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | BMPR1B Rabbit Polyclonal Antibody detects endogenous levels of BMPR1B protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
BMPR1B also known as BMPR-IB, ALK6 is a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. BMPR1B plays a crucial role in the bone morphogenetic protein (BMP) signaling pathway, which regulates various biological processes, including cell differentiation, proliferation, and apoptosis. BMPR1B is primarily located on the cell membrane, where BMPR1B interacts with BMPs to form a signaling complex that activates downstream serine/threonine kinases. Proper functioning of BMPR1B is vital for maintaining normal bone development and homeostasis, as dysregulation of this pathway can lead to various pathologies, including cancer and bone disorders. BMPR1B is expressed in several tissues, including the brain and human glioma cell lines, highlighting BMPR1B′s importance in both normal physiology and disease states. |
| Product Image Gallery | |
 Western blot analysis of extracts on U251MG, Mouse kidney cells, using BMPR1B Rabbit Polyclonal Antibody (EAB13704) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
 Immunohistochemistry of paraffin-embedded Human placenta tissue, using BMPR1B Rabbit Polyclonal Antibody (EAB13704) at 1:100 dilution.
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