| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 115 | Human, Mouse, Rat, Monkey |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | BMPR2 Rabbit Polyclonal Antibody detects endogenous levels of BMPR2 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
BMPR2 also known as BMPR-II is a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. BMPR2 plays a crucial role in the bone morphogenetic protein (BMP) signaling pathway, which regulates various biological processes such as cell differentiation, proliferation, and apoptosis. BMPR2 functions as a type II receptor that interacts with type I receptors, BMPR-IA and BMPR-IB, forming a signaling complex that mediates BMP effects on gene expression and morphogenesis. BMPR2 expression occurs in various tissues, including the brain, where proper functioning maintains normal physiological processes. Dysregulation of BMPR2 signaling has been linked to several diseases, including pulmonary arterial hypertension and certain types of cancer, making BMPR2 an important target for therapeutic intervention. |
| Product Image Gallery | |
 Western blot analysis of extracts on HuvEc, Mouse brain cells, using BMPR2 Rabbit Polyclonal Antibody (EAB13705) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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