| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IF/ICC, ELISA | 80 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IF/ICC=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | C1R Rabbit Polyclonal Antibody detects endogenous levels of C1R protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
C1R also known as Complement C1Ris a member of the peptidase S1 protein family. C1R plays a vital role in the activation of the classical complement pathway. This pathway is essential for the immune response, as C1R helps to opsonize pathogens, promote inflammation, and facilitate the clearance of immune complexes. C1R exists as a dimer, which is activated through cleavage into two chains, A and B, allowing C1R to interact with C1Q and C1S to form the C1 complex. This complex is pivotal for initiating the complement cascade, leading to the generation of anaphylatoxins that enhance the inflammatory response. Understanding the structure and function of C1R is important, as dysregulation of the complement system can lead to various autoimmune diseases and inflammatory conditions. |
| Product Image Gallery | |
 Western blot analysis of extracts on Mouse bone marrow cells, using C1R Rabbit Polyclonal Antibody (EAB13713) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
|
