CCL22 Rabbit Polyclonal Antibody
Catalog #:EAB13723
Host / Isotype Clonality Applications MW (kDa) Reactivity
Rabbit IgG Polyclonal WB, ELISA 11 Human, Mouse
Application Key

WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry

Reactivity Key

H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Applications Dilutions
The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user.
WB(Westem Blotting)
IHC-P(Immunohistochemistry-Paraffin)
IF/ICC(Immunofluorescence/Immunocytochemistry)
ELISA(Enzyme-linked Immunosorbent Assay)
WB=1:500-2000 
Product Information
Conjugate Unconjugate
Specificity CCL22 Rabbit Polyclonal Antibody detects endogenous levels of CCL22 protein.
Purification Affinity purification
Concentration 1mg/ml
Format Liquid
Formulation In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping Gel Pack
Storage Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
UniProt ID

O00626

Entrez Gene ID

6367

Product Description

CCL22 also known as MDC is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. plays a crucial role in immune response, particularly in chronic inflammation and recruitment of immune cells to sites of tissue damage or infection. CCL22 protein is primarily expressed in thymus and spleen, where CCL22 protein facilitates homing of dendritic cells and lymphocytes, thereby influencing adaptive immune response. CCL22 protein interaction with high-affinity receptor, CCR4, predominantly found on T helper type 2 polarized cells, underscores importance in directing lymphocyte trafficking and modulating immune responses. This chemokine is particularly significant in systemic immunity, as CCL22 protein helps guide T cells to areas where needed most, such as inflamed tissues.

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For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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