CD79B Rabbit Polyclonal Antibody
Catalog #:EAB13742
Host / Isotype Clonality Applications MW (kDa) Reactivity
Rabbit IgG Polyclonal WB, IHC-P, IF, ELISA 26 Human, Mouse, Rat
Applications Dilutions
The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user.
WB=1:500-2000 
IHC-P=1:50-300 
IF=1:50-300 
Application Key

WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry

Reactivity Key

H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Information
Conjugate Unconjugate
Specificity CD79B Rabbit Polyclonal Antibody detects endogenous levels of CD79B protein.
Purification Affinity purification
Concentration 1mg/ml
Format Liquid
Formulation In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping Gel Pack
Storage Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
UniProt ID

P40259

Entrez Gene ID

974

Product Description

CD79B also known as B29, Igbeta is a critical component of the B cell antigen receptor complex, functioning alongside CD79A to facilitate the signaling necessary for B cell activation and development. CD79B contains a cytoplasmic tail with an immuno-receptor tyrosine-based activation motif (ITAM) that is essential for initiating downstream signaling cascades upon antigen binding. This activation is crucial for B cell proliferation, differentiation, and the production of antibodies, making CD79B a vital player in adaptive immunity. The interaction of CD79B with membrane immunoglobulins, such as IgM and IgD, not only aids in their surface expression but also enhances their ability to present antigens effectively, thereby ensuring a robust immune response.

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For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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