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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 192 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 | |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Clathrin heavy chain/CLTC Rabbit Polyclonal Antibody detects endogenous levels of Clathrin heavy chain/CLTC protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Clathrin is a crucial cytosolic coat protein. Clathrin plays a significant role in receptor-mediated endocytosis, facilitating the engulfing of receptor proteins by clathrin-coated vesicles. Clathrin′s structure consists of three heavy chains and three light chains that non-covalently associate to form a distinctive triskelion shape. This triskelion structure is essential for Clathrin′s function, as the proximal segment of the heavy chain contains a binding site for light chains, critical for the assembly and stability of the clathrin coat. Proper formation of this coat enables efficient internalization of membrane proteins and lipids, influencing various cellular processes, including nutrient uptake and signal transduction. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, NIH/3T3 cells, using Clathrin heavy chain/CLTC Rabbit Polyclonal Antibody (EAB13761) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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