| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF/ICC, ELISA | 53 | Human, Mouse, Rat, Monkey |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-300 IF/ICC=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | CNR1/CB1 Rabbit Polyclonal Antibody detects endogenous levels of CNR1/CB1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
CNR1(Cannabinoid receptor 1) also known as CB1 is a members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner.. CNR1 plays a crucial role in modulating neurotransmitter release and influencing various physiological processes. CNR1 localization in the central nervous system is particularly important as CNR1 is involved in the regulation of pain, mood, appetite, and memory, making CNR1 a significant target for therapeutic interventions in conditions such as chronic pain, anxiety, and neurodegenerative diseases. CNR1 undergoes post-translational modifications, including phosphorylation, which can affect CNR1 activity and interactions with other proteins. |
| Product Image Gallery | |
 Western blot analysis of extracts on COS7, HT29 cells, using CNR1/CB1 Rabbit Polyclonal Antibody (EAB13764) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
 Immunohistochemistry of paraffin-embedded Human brain tissue, using CNR1/CB1 Rabbit Polyclonal Antibody (EAB13764) at 1:100 dilution.
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