| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 88 | Human, Mouse, Rat, Canine |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | CPT1A Rabbit Polyclonal Antibody detects endogenous levels of CPT1A protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
CPT1A is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. CPTI plays a crucial role in mitochondrial β-oxidation of long-chain fatty acids, initiating fatty acid transport from cytoplasm into mitochondrion, which is a rate-limiting step in the metabolic pathway. This process is essential for energy production, particularly in tissues that rely heavily on fatty acid oxidation, such as heart and skeletal muscle. CPTI exists in two isoforms: CPT1A, predominantly expressed in liver, and CPT1B, specifically found in muscle tissues. Membrane-bound CPTI is reversibly inhibited by malonyl-coenzyme A, highlighting regulatory mechanisms that control fatty acid metabolism. |
| Product Image Gallery | |
 Western blot analysis of extracts on 293T, Raw264.7 cells, using CPT1A Rabbit Polyclonal Antibody (EAB13776) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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