WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry

Cathepsin B also known as CTSB is a member of the C1 family of peptidases. plays a crucial role in protein degradation and is involved in various cellular processes, including apoptosis and antigen processing. Expression in luminal epithelial cells highlights cathepsin B′s significance as a marker for secretory cell death, making cathepsin B an important target for studies related to cancer and other diseases where cell death is a critical factor. Understanding cathepsin B function is vital, as dysregulation can lead to pathological conditions, including tumor progression and metastasis. Cathepsin B′s ability to activate other proteases and involvement in extracellular matrix remodeling further underscore cathepsin B′s importance in both normal physiology and disease states.