| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF/ICC, ELISA | 164 | Human, Mouse |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-300 IF/ICC=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | CUTL1 Rabbit Polyclonal Antibody detects endogenous levels of CUTL1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
CUTL1 also known as CUX1, CDP is a crucial homeodomain-containing transcriptional repressor located predominantly in the nucleus, where CDP regulates the transcription of developmentally controlled genes by competing with transcriptional activators for binding to promoter regions. CDP is a key component of the HiNF-D complex, which includes cyclin A, Cdc2, and an Rb-related protein. This complex is vital for the regulation of histone gene transcription, specifically histones H4, H3, and H1, which are necessary for chromatin assembly and the progression of cells from the G1 phase to the S phase of the cell cycle. By controlling histone expression, CDP plays an integral role in ensuring genomic integrity and facilitating proper cell division. |
| Product Image Gallery | |
 Western blot analysis of extracts on 293T, K562 cells, using CUTL1 Rabbit Polyclonal Antibody (EAB13914) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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