| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 12 | Human |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Dermcidin Rabbit Polyclonal Antibody detects endogenous levels of Dermcidin protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Dermcidin also known as DCD plays a crucial role in the innate immune response by producing antimicrobial peptides, particularly DCD-1, which is secreted from sweat glands and acts as a first line of defense against pathogenic microorganisms. This antimicrobial activity is vital for maintaining skin integrity and preventing infections, especially in areas prone to moisture. Notably, Dermcidin expression is not only essential for skin health but has also been implicated in breast cancer, where overexpression can enhance cell proliferation and survival, often associated with a focal copy number gain on chromosome 12q13.2. Dermcidin′s ability to modulate immune responses and involvement in cancer biology make this protein a significant target for research and therapeutic applications. |
| Product Image Gallery | |
 Western blot analysis of extracts on Mouse skin cells, using Dermcidin Rabbit Polyclonal Antibody (EAB13816) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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