| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 34 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | DNASE1L1 Rabbit Polyclonal Antibody detects endogenous levels of DNASE1L1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
DNASE1L1(Deoxyribonuclease I-like 1) also known as XIB, DNL1L, DNASEX is a deoxyribonuclease protein that shows high sequence similarity to DNase I. DNASE1L1 plays a crucial role in DNA degradation, particularly during apoptosis, by mediating internucleosomal DNA fragmentation through catalytic activity. This function is vital for maintaining cellular homeostasis and preventing damaged DNA accumulation, which can lead to various diseases, including cancer. DNASE1L1 is predominantly localized in the endoplasmic reticulum and is expressed at high levels in cardiac and skeletal muscle, with lower expression in other tissues, highlighting importance in muscle physiology and development. |
| Product Image Gallery | |
 Western blot analysis of extracts on Mouse heart cells, using DNASE1L1 Rabbit Polyclonal Antibody (EAB11127) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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