DRD1 Rabbit Polyclonal Antibody
Catalog #:EAB13835
Host / Isotype Clonality Applications MW (kDa) Reactivity
Rabbit IgG Polyclonal WB, IHC-P, IF/ICC, ELISA 50 Human, Mouse, Rat
Applications Dilutions
The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user.
WB=1:500-2000 
IHC-P=1:50-300 
IF/ICC=1:50-300 
Application Key

WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry

Reactivity Key

H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Information
Conjugate Unconjugate
Specificity DRD1 Rabbit Polyclonal Antibody detects endogenous levels of DRD1 protein.
Purification Affinity purification
Concentration 1mg/ml
Format Liquid
Formulation In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping Gel Pack
Storage Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
UniProt ID

P21728

Entrez Gene ID

1812

Product Description

DRD1(Dopamine receptor D1) is a D1 subtype of the dopamine receptor. DRD1 plays a crucial role in the central nervous system by mediating dopamine effects, a key neurotransmitter involved in regulating mood, cognition, and motor control. Proper functioning of D1DR is essential for maintaining neurological health, as dysregulation of dopamine signaling has been implicated in several neuropsychiatric disorders, including schizophrenia and Parkinson′s disease. Located primarily in the brain, particularly in areas such as the striatum and prefrontal cortex, D1DR′s strategic positioning allows for influence on neuronal signaling pathways and synaptic plasticity, which are vital for learning and memory processes. D1DR undergoes various post-translational modifications, including phosphorylation, which can modulate activity and interactions with other proteins, thereby affecting downstream signaling cascades.

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For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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