| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 177 | Human, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | DUOX1 Rabbit Polyclonal Antibody detects endogenous levels of DUOX1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
DUOX1(Dual oxidase 1) is a glycoprotein and a member of the NADPH oxidase family. DUOX1 is primarily located in the airway epithelium and plays a critical role in generating reactive oxygen species (ROS), which are essential for various physiological processes. DUOX1 is predominantly expressed in thyrocytes and tracheal surface epithelial cells, as well as in the thyroid, trachea, and bronchial tissues. The generation of hydrogen peroxide by DUOX1 is vital for the activity of thyroid peroxidase and lactoperoxidase, both of which are crucial for thyroid hormone synthesis and antimicrobial defense in mucosal tissues. Additionally, DUOX1 is involved in mucin expression, highlighting DUOX1′s importance in maintaining airway health and function. |
| Product Image Gallery | |
 Western blot analysis of extracts on MCF7 cells, using DUOX1 Rabbit Polyclonal Antibody (EAB13839) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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