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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 83 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | FoxM1 Rabbit Polyclonal Antibody detects endogenous levels of FoxM1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
FoxM1(Forkhead box M1) also known as FKHL16, HFH11, INS-1, PIG29 is a critical transcription factor located predominantly in the nucleus of proliferating cells, where FOXM1 plays an essential role in regulating the expression of genes involved in cell cycle progression, particularly the transition from G1 to S phase and mitotic entry by activating key cell cycle regulators like cyclin B1, cyclin D1, and Cdc25B. Nuclear localization of FOXM1 is vital for controlling cellular proliferation, DNA replication, and repair processes, making FOXM1 a key player in maintaining normal cell growth and tissue regeneration. Dysregulation of FOXM1, often resulting in overexpression, is closely associated with various cancers, as FOXM1 can lead to uncontrolled cell division and tumor progression. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, Mouse brain cells, using FoxM1 Rabbit Polyclonal Antibody (EAB10760) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 83 kDa; Observed band size: 110 kDa |
