FSHR Rabbit Polyclonal Antibody
Catalog #:EAB13887
Host / Isotype Clonality Applications MW (kDa) Reactivity
Rabbit IgG Polyclonal WB, IHC-P, IF, ELISA 78 Human, Mouse, Rat
Applications Dilutions
The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user.
WB=1:500-2000 
IHC-P=1:50-300 
IF=1:50-300 
Application Key

WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry

Reactivity Key

H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Information
Conjugate Unconjugate
Specificity FSHR Rabbit Polyclonal Antibody detects endogenous levels of FSHR protein.
Purification Affinity purification
Concentration 1mg/ml
Format Liquid
Formulation In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping Gel Pack
Storage Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
UniProt ID

P23945

Entrez Gene ID

2492

Product Description

FSHR(Follicle stimulating hormone receptor) belongs to family 1 of G-protein coupled receptors. It is the receptor for follicle stimulating hormone and functions in gonad development that primarily couples to Gs proteins to stimulate cAMP/PKA signaling following ligand engagement, shaping transcriptional programs that control gonadal cell differentiation, steroidogenesis, and folliculogenesis. Receptor activation interfaces with broader GPCR regulatory processes including receptor desensitization, internalization, and downstream MAPK signaling dynamics that influence proliferation and endocrine responsiveness. Altered FSHR expression or signaling is associated with reproductive endocrine phenotypes such as ovarian dysfunction, variable gonadotropin sensitivity, and impaired fertility, and it is also used as a marker of hormone-responsive cellular states.

 

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For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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