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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF/ICC, ELISA | 23 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 IF/ICC=1:50-300 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Frataxin/FXN Rabbit Polyclonal Antibody detects endogenous levels of Frataxin/FXN protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Frataxin also known as FXN is a mitochondrial protein which belongs to the FRATAXIN family. Frataxin plays a crucial role in mitochondrial function, particularly in iron metabolism. Frataxin assembles into a stable homopolymer with remarkable iron-binding capabilities, capable of binding up to 10 iron atoms per molecule when expressed in E. coli. This iron-storage function is vital for maintaining mitochondrial health, as iron is essential for various cellular processes, including energy production through oxidative phosphorylation. Frataxin acts as an activator of oxidative phosphorylation, enhancing mitochondrial membrane potential and increasing cellular ATP levels. |
| Product Image Gallery | |
 Western blot analysis of extracts on Raji, Jurkat, Mouse heart cells, using Frataxin/FXN Rabbit Polyclonal Antibody (EAB13890) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 23 kDa; Observed band size: 14 kDa |
