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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF, ELISA | 18 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 IF=1:50-300 |
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| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Phospho-Pin1 (Ser16) Rabbit Polyclonal Antibody detects endogenous levels of Pin1 protein only when phosphorylated at Ser16. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Pin1 also known as UBL5 is a crucial enzyme characterized by its unique structure, which includes a WW domain responsible for binding phosphorylated serine/threonine-proline motifs and a peptidylprolyl isomerase (PPIase) domain that catalyzes the cis/trans isomerization of proline residues. This structural configuration enables Pin1 to regulate the conformation and function of its substrates, playing a vital role in controlling cell cycle progression, signal transduction, and protein stability. Proper functioning of Pin1 is essential for maintaining cellular homeostasis, and dysregulation has been implicated in various diseases, including cancer and neurodegenerative disorders. |
| Product Image Gallery | |
 Western blot analysis of extracts on COS7 cells treated with Insulin, using Phospho-Pin1 (Ser16) Rabbit Polyclonal Antibody (EAB13899) at 1:1000 dilution. The lane on the left is blocked with the phospho peptide.
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