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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 93 | Human, Mouse |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 |
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| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Periostin Rabbit Polyclonal Antibody detects endogenous levels of Periostin protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Periostin also known as OSF2, POSTN is a secreted extracellular matrix protein that functions in tissue development and regeneration, including wound healing, and ventricular remodeling following myocardial infarction. Periostin plays a crucial role in cell adhesion and migration, particularly in bone and tissue remodeling. Periostin serves as a ligand for alpha(V)beta(3) and alpha(V)beta(5) integrins, facilitating osteoblast recruitment and attachment, essential for bone formation and repair. Periostin is predominantly found in the lower gastrointestinal tract, aorta, stomach, placenta, uterus, and breast tissues, with notable up-regulation in epithelial ovarian tumors and overexpression in breast cancer, highlighting potential roles in tumor progression and metastasis. Periostin expression is influenced by bone morphogenetic protein 2 (BMP2) and transforming growth factor beta 1 (TGF β 1), indicating involvement in various signaling pathways that regulate cellular processes. |
| Product Image Gallery | |
 Western blot analysis of extracts on Rat kidney cells, using Periostin Rabbit Polyclonal Antibody (EAB13920) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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