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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 25 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | PRG2 Rabbit Polyclonal Antibody detects endogenous levels of PRG2 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
PRG2(Proteoglycan 2) also known as MBP, EMBP, BMPG is the predominant constituent of the crystalline core of the eosinophil granule. PRG2 plays a significant role in the immune response. PRG2 is primarily located in eosinophils, which are white blood cells involved in combating parasitic infections and mediating allergic reactions. The presence of PRG2 in eosinophils is crucial for their cytotoxic activity against helminths and contributes to the pathophysiology of various allergic diseases. Additionally, PRG2 is known to interact with other proteins, such as pregnancy-associated plasma protein A (PAPPA), angiotensinogen (AGT), and C3dg, particularly during pregnancy, where it forms complexes that may influence immune responses. |
| Product Image Gallery | |
 Western blot analysis of extracts on THP-1, K562, Jurkat cells, using PRG2 Rabbit Polyclonal Antibody (EAB13927) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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