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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF, ELISA | 26 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 IF=1:50-300 |
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| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | PRL Rabbit Polyclonal Antibody detects endogenous levels of PRL protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
PRL also known as Prolactin is a 226 amino acid protein, is primarily secreted by the anterior pituitary gland and plays a crucial role in numerous physiological processes, including cell growth, reproduction, and immune regulation. Notably, Prolactin is secreted by endothelial cells during angiogenesis and has been implicated in mammary cancer development, acting as both a mitogen and a differentiating agent. Prolactin enhances B cell hybridoma proliferation, significantly contributing to increased antibody production and immune responses. Additionally, Prolactin counteracts the antiproliferative effects of immunosuppressive cytokine TGF-beta, linking Prolactin to various autoimmune diseases such as arthritis and type 1 diabetes. With diverse roles in health and disease, Prolactin continues to be a vital target for research and therapeutic applications. |
| Product Image Gallery | |
 Western blot analysis of extracts on SKOV3, Mouse heart cells, using PRL Rabbit Polyclonal Antibody (EAB13929) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
 Immunohistochemical analysis of paraffin-embedded Human brain tissue, using PRL Rabbit Polyclonal Antibody (EAB13929) at 1:100 dilution.
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