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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 24 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 | |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Rab11A Rabbit Polyclonal Antibody detects endogenous levels of Rab11A protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Rab11A also known as YL8 is a member of the Rab family of small GTPases that regulate intracellular vesicle trafficking, particularly in the recycling endosome pathway. Post-translationally modified by prenylation through geranylgeranylation at C-terminal cysteine residues, Rab11A requires this lipid modification for proper membrane association and function in vesicle formation, movement, and fusion. These post-translational modifications are crucial as they facilitate Rab11A′s localization to specific membrane compartments, influencing essential cellular processes such as receptor recycling, cytokinesis, and maintenance of cell polarity. Dysregulation or mutations affecting Rab11A or its post-translational modifications can lead to disruptions in cellular trafficking pathways, contributing to various diseases. |
| Product Image Gallery | |
 Western blot analysis of extracts on MCF7, Jurkat cells, using Rab11A Rabbit Polyclonal Antibody (EAB13940) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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