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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF/ICC, ELISA | 565 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 IF/ICC=1:50-300 |
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| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | RyR2 Rabbit Polyclonal Antibody detects endogenous levels of RyR2 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
RyR2(Ryanodine receptor 2) is member of the ryanodine receptor family. RyR2 is a ryanodine receptor found in cardiac muscle sarcoplasmic reticulum. RyR2 protein is one of the components of a calcium channel, composed of a tetramer of the ryanodine receptor proteins and a tetramer of FK506 binding protein 1B proteins, that supplies calcium to cardiac muscle. Mutations in RyR2 are associated with stress-induced polymorphic ventricular tachycardia and arrhythmogenic right ventricular dysplasia. Defects in RYR2 are the cause of familial arrhythmogenic right ventricular dysplasia type 2 which known as arrhythmogenic right ventricular cardiomyopathy 2. Defects in RYR2 are the cause of catecholaminergic polymorphic ventricular tachycardia type 1 which known as stress-induced polymorphic ventricular tachycardia. |
| Product Image Gallery | |
 Western blot analysis of extracts on HepG2, PC3, Mouse brain cells, using RyR2 Rabbit Polyclonal Antibody (EAB11614) at 1:2000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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