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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 10 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | S100A12 Rabbit Polyclonal Antibody detects endogenous levels of S100A12 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
S100A12 also known as Calgranulin C, CGRP, EN-RAGE is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100A12 plays a crucial role in immune response, particularly in the activation and recruitment of immune cells during inflammation. S100A12 is primarily expressed in macrophages and epithelial cells, where S100A12 acts as a pro-inflammatory mediator, influencing the behavior of various immune cells and contributing to the pathophysiology of several inflammatory diseases. The ability of S100A12 to interact with specific proteins, such as receptor for advanced glycation end products (RAGE), underscores its importance in cellular signaling pathways that regulate inflammation and tissue repair. |
| Product Image Gallery | |
 Western blot analysis of extracts on A431 cells, using S100A12 Rabbit Polyclonal Antibody (EAB13974) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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