| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 30 | Human, Mouse |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | SCO2 Rabbit Polyclonal Antibody detects endogenous levels of SCO2 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
SCO2 is one of the COX assembly factors. SCO2 protein is a metallochaperone that is involved in the biogenesis of cytochrome c oxidase subunit II. SCO2 is a mitochondrial inner membrane-associated metallochaperone required for cytochrome c oxidase (complex IV) biogenesis by delivering copper to the COX2 subunit and supporting assembly of the respiratory chain. Through its role in oxidative phosphorylation, SCO2 helps maintain mitochondrial membrane potential, ATP production, and redox homeostasis, linking it to cellular energy metabolism and stress responses. Disruption of SCO2 impairs complex IV activity and can shift cells toward altered metabolic states, impacting processes such as reactive oxygen species handling and apoptosis sensitivity. |
| Product Image Gallery | |
 Western blot analysis of extracts on Caski, SW480 cells, using SCO2 Rabbit Polyclonal Antibody (EAB13969) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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