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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 37 | Human, Mouse |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 | |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | SLAMF7/CD319 Rabbit Polyclonal Antibody detects endogenous levels of SLAMF7/CD319 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
SLAMF7 also known as CS1, CRACC, CD19 is a homophilic cell surface receptor belonging to the signaling lymphocytic activation molecule (SLAM) family, predominantly expressed on natural killer (NK) cells, T cells, and activated B cells. SLAMF7 plays a crucial role in immune responses, particularly in the activation of NK cells, which are essential for the body′s defense against tumors and virally infected cells. SLAMF7′s unique structure includes immunoreceptor tyrosine-based switch motifs in its cytoplasmic domain, allowing SLAMF7 to engage in signaling pathways that enhance cytotoxic activity. Notably, SLAMF7 activates NK cells through an EAT-2-mediated pathway that is independent of SLAM-associated protein (SAP), distinguishing SLAMF7 from other SLAM receptors. |
| Product Image Gallery | |
 Western blot analysis of extracts on DU145, Mouse lung cells, using SLAMF7/CD319 Rabbit Polyclonal Antibody (EAB13985) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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