
| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF, ELISA | 53 | Human, Mouse |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 IF=1:50-300 |
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| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | TFEB Rabbit Polyclonal Antibody detects endogenous levels of TFEB protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
TFEB also known as TCFEB is a member of the basic helix-loop-helix (bHLH) transcription factor family. TFEB plays a crucial role in cellular processes such as autophagy and lysosomal biogenesis, which are vital for maintaining cellular homeostasis and responding to stress. TFEB′s ability to regulate gene expression in response to nutrient availability and cellular stress highlights its importance in metabolic regulation and potential implications in diseases such as cancer and neurodegeneration. TFEB is predominantly expressed in trophoblast cells of the placenta, where TFEB is essential for normal vascularization, and can form homodimers or heterodimers with other related proteins like TFE3 and TFEC, further influencing regulatory functions. |
| Product Image Gallery | |
![]() Western blot analysis of extracts on Jurkat, Mouse lung cells, using TFEB Rabbit Polyclonal Antibody (EAB14033) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
![]() Immunohistochemistry analysis of paraffin-embedded Human lung carcinoma tissue, using TFEB Rabbit Polyclonal Antibody (EAB14033) at 1:100 dilution.
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