TFEB Rabbit Polyclonal Antibody
Catalog #:EAB14033
Host / Isotype Clonality Applications MW (kDa) Reactivity
Rabbit IgG Polyclonal WB, IHC-P, IF, ELISA 53 Human, Mouse
Applications Dilutions
The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user.
WB=1:500-2000 
IHC-P=1:50-300 
IF=1:50-300 
Application Key

WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry

Reactivity Key

H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Information
Conjugate Unconjugate
Specificity TFEB Rabbit Polyclonal Antibody detects endogenous levels of TFEB protein.
Purification Affinity purification
Concentration 1mg/ml
Format Liquid
Formulation In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping Gel Pack
Storage Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
UniProt ID

P19484

Entrez Gene ID

7942

Product Description

TFEB also known as TCFEB is a member of the basic helix-loop-helix (bHLH) transcription factor family. TFEB plays a crucial role in cellular processes such as autophagy and lysosomal biogenesis, which are vital for maintaining cellular homeostasis and responding to stress. TFEB′s ability to regulate gene expression in response to nutrient availability and cellular stress highlights its importance in metabolic regulation and potential implications in diseases such as cancer and neurodegeneration. TFEB is predominantly expressed in trophoblast cells of the placenta, where TFEB is essential for normal vascularization, and can form homodimers or heterodimers with other related proteins like TFE3 and TFEC, further influencing regulatory functions.

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For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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