| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 35 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | TFPI Rabbit Polyclonal Antibody detects endogenous levels of TFPI protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
TFPI(Tissue factor pathway inhibitor) is a Kunitz-type serine protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation.TFPI plays a crucial role in regulating the extrinsic pathway of blood coagulation, which is vital for maintaining hemostasis and preventing excessive bleeding. TFPI functions by directly inhibiting factor Xa and, in an Xa-dependent manner, also inhibits the catalytic complex formed by factor VIIa and tissue factor, thereby preventing the propagation of coagulation. This regulation is particularly important in pathological conditions where tissue factor is aberrantly expressed, such as in cancer and inflammatory diseases, as TFPI helps to control thrombus formation and maintain vascular integrity. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, HepG2 cells, using TFPI Rabbit Polyclonal Antibody (EAB14034) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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