www.ebiocell.com
| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF, ELISA | 47 | Human, Mouse, Rat, Monkey |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 IF=1:50-300 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | TGF-β3 Rabbit Polyclonal Antibody detects endogenous levels of TGF-β3 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
TGF-β3 also known as TGF beta3, TGFB3 is essential for proper embryonic development and tissue homeostasis, mediating intercellular signaling that influences cell fate decisions during development. TGFβ3 is synthesized as a precursor protein, cleaved to produce a 112 amino acid polypeptide, which remains associated with a latent portion of the molecule, highlighting complex regulation and function. TGFβ3 expression levels are significant in various pathological conditions, showing overexpression in extramammary Paget′s disease and downregulation in Bowen′s disease, making TGFβ3 a valuable biomarker for tumor activity. TGFβ3 levels correlate strongly with insulin-like growth factor 1 and osteocalcin levels in serum, suggesting involvement in bone metabolism and potential implications in bone-related diseases. |
| Product Image Gallery | |
 Western blot analysis of extracts on COS7 cells, using TGF-β3 Rabbit Polyclonal Antibody (EAB14036) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 47 kDa; Observed band size: 13 kDa |
