| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF/ICC, ELISA | 24 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-300 IF/ICC=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | TIMP2 Rabbit Polyclonal Antibody detects endogenous levels of TIMP2 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
TIMP2 also known as DDC8 is a member of the TIMP gene family. TIMP2 plays a crucial role in regulating extracellular matrix remodeling by inhibiting metalloproteinases, which are enzymes responsible for the degradation of various components of the extracellular matrix. This regulation is vital for maintaining tissue homeostasis and facilitating processes such as wound healing and embryonic development. Notably, TIMP2 interacts with matrix metalloproteinases (MMPs) like MMP-2 and MMP-9, effectively preventing excessive tissue breakdown and promoting cellular stability. TIMP2 expression is particularly important in various physiological and pathological contexts, including cancer progression, where TIMP2 levels can influence tumor growth and metastasis. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, A549 cells, using TIMP2 Rabbit Polyclonal Antibody (EAB14042) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
 Immunohistochemical analysis of paraffin-embedded Human colon tissue, using TIMP2 Rabbit Polyclonal Antibody (EAB14042) at 1:200 dilution.
 Immunohistochemical analysis of paraffin-embedded Human kidney tissue, using TIMP2 Rabbit Polyclonal Antibody (EAB14042) at 1:200 dilution.
 Immunofluorescence analysis of A549 cell, using TIMP2 Rabbit Polyclonal Antibody (EAB14042) at 1:200 dilution.
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