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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 116 | Human, Mouse |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 | |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Toll-like receptor 9/TLR9 Rabbit Polyclonal Antibody detects endogenous levels of Toll-like receptor 9/TLR9 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
TLR9(Toll-like receptor 9) is a member of the Toll-like receptor (TLR) family. TLR9 plays a crucial role in the innate immune system by recognizing specific unmethylated CpG motifs found in bacterial and viral DNA, which is essential for initiating an immune response. This recognition triggers the activation of signaling pathways that lead to the production of pro-inflammatory cytokines, thereby enhancing the host′s ability to combat infections. TLR9 is predominantly located in immune cells such as dendritic cells and B cells, particularly in the spleen, lymph nodes, and bone marrow, where TLR9 acts as a sentinel for pathogen detection. The strategic localization of TLR9 in these immune-rich tissues underscores TLR9′s importance in orchestrating the body′s defense mechanisms against pathogens. |
| Product Image Gallery | |
 Western blot analysis of extracts on Mouse spleen cells, using Toll-like receptor 9/TLR9 Rabbit Polyclonal Antibody (EAB14433) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 116 kDa; Observed band size: 125 kDa |
