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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 106 | Human, Mouse |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | TRPC6 Rabbit Polyclonal Antibody detects endogenous levels of TRPC6 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
TRPC6 also known as TRP6 consists of 931 amino acids and is part of a larger superfamily of TRP channels that are vital for maintaining calcium homeostasis and responding to physiological stimuli. TRPC6 plays a crucial role in mediating store-operated calcium entry, which is essential for various cellular functions, including muscle contraction, neurotransmitter release, and cell proliferation. TRPC6 is primarily located in the plasma membrane of cells in tissues such as the placenta, spleen, lung, small intestine, and ovary, where TRPC6 facilitates the influx of calcium ions in response to diacylglycerol activation. The gene encoding human TRPC6 is located on chromosome 11q21-q22, and TRPC6 function is critical for various signaling pathways, making TRPC6 a significant target for research in cardiovascular and neurological disorders. |
| Product Image Gallery | |
 Western blot analysis of extracts on SW480 cells, using TRPC6 Rabbit Polyclonal Antibody (EAB14070) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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