www.ebiocell.com
| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 87 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 | |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | TSHR Rabbit Polyclonal Antibody detects endogenous levels of TSHR protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
TSHR also known as LGR3, Thyrotropin Receptor is a membrane protein and a major controller of thyroid cell metabolism. TSHR plays a crucial role in regulating thyroid function by mediating the effects of thyroid-stimulating hormone (TSH), which is essential for maintaining thyroid structure and metabolism. TSHR is located on the surface of thyroid follicular cells, where TSH binding leads to the activation of intracellular signaling pathways that stimulate the production and release of thyroid hormones. Such regulation is vital for numerous physiological processes, including metabolism, growth, and development. TSHR undergoes post-translational modifications, such as glycosylation, which are important for stability, localization, and function. These modifications can influence receptor activity and are critical for proper signaling, highlighting TSHR′s importance in endocrine health. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, Mouse thymus cells, using TSHR Rabbit Polyclonal Antibody (EAB14076) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
|
