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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 22 | Human, Mouse |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 | |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | TWIST1 Rabbit Polyclonal Antibody detects endogenous levels of TWIST1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
TWIST1 is a basic helix-loop-helix (bHLH) transcription factor that plays a crucial role in regulating mesodermal differentiation and myogenesis, making twist essential for proper muscle development. twist protein is primarily expressed in the epithelial somite, where twist acts as a negative regulator of myogenic regulatory factors by dimerizing with E proteins, thereby inhibiting their function. This regulatory mechanism is vital for the temporal and spatial formation of myotomes, as twist ensures that muscle tissue develops correctly from the embryonic mesoderm. twist interaction with other proteins in the myogenic determination family highlights twist importance in muscle cell lineage specification and differentiation, underscoring twist significance in developmental biology and potential implications in muscle-related disorders. |
| Product Image Gallery | |
 Western blot analysis of extracts on Jurkat cells, using TWIST1 Rabbit Polyclonal Antibody (EAB14079) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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