| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF, ELISA | 25 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-300 IF=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | UCHL1 Rabbit Polyclonal Antibody detects endogenous levels of UCHL1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
UCHL1 also known as PGP9.5 is a member of the peptidase C12 family. UCHL1 plays a crucial role in the ubiquitin-proteasome pathway by hydrolyzing small C-terminal adducts of ubiquitin to release free ubiquitin monomers, which are essential for protein degradation and cellular regulation. UCHL1 is predominantly expressed in neurons and cells of the diffuse neuroendocrine system, with significant localization in brain regions such as the substantia nigra, where UCHL1 constitutes 1-2% of total soluble brain protein. UCHL1′s presence in Lewy bodies highlights UCHL1′s potential involvement in neurodegenerative diseases, particularly Parkinson′s disease, making UCHL1 a valuable target for research. |
| Product Image Gallery | |
 Western blot analysis of extracts on U251, Mouse brain cells, using UCHL1 Rabbit Polyclonal Antibody (EAB14083) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
 Immunohistochemical analysis of paraffin-embedded Human liver tissue, using UCHL1 Rabbit Polyclonal Antibody (EAB14083) at 1:200 dilution.
 Immunohistochemical analysis of paraffin-embedded Human kidney tissue, using UCHL1 Rabbit Polyclonal Antibody (EAB14083) at 1:200 dilution.
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