www.ebiocell.com
| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 33 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 | |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | UCP1 Rabbit Polyclonal Antibody detects endogenous levels of UCP1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
UCP1 also known as SLC25A7 is an integral membrane protein predominantly found in brown adipose tissue mitochondria, where UCP1 plays a crucial role in thermogenesis. UCP1 functions by forming a dimer that acts as a proton channel, allowing protons to re-enter the mitochondrial matrix without generating ATP, thereby dissipating the electrochemical gradient and producing heat instead. This process maintains body temperature in cold environments and links intricately to energy expenditure and glucose metabolism. UCP1 activity regulation is essential for metabolic health, as UCP1 influences the balance between energy storage and expenditure, making UCP1 a significant target for research into obesity and metabolic disorders. |
| Product Image Gallery | |
 Western blot analysis of extracts on HCT116 cells, using UCP1 Rabbit Polyclonal Antibody (EAB14084) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
|
