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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF, ELISA | 53 | Human, Mouse |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 IF=1:50-300 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Phospho-WASP (Tyr290) Rabbit Polyclonal Antibody detects endogenous levels of WASP protein only when phosphorylated at Tyr290. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
WASP is a genetic disorder linked to a mutation on the short arm of the X chromosome, characterized by symptoms such as thrombocytopenia, eczema, immune deficiencies, and an increased risk of lymphoproliferative diseases. The gene responsible for WAS encodes WASP, a proline-rich protein that plays a crucial role in cytoskeletal organization. WASP is involved in the regulation of actin polymerization, which is essential for various cellular processes, including cell motility, shape, and division. A Cdc42/Rac interacting domain in WASP sequence indicates function as a downstream effector of Cdc42, a small GTPase that orchestrates cytoskeleton reorganization in response to extracellular signals. |
| Product Image Gallery | |
 Western blot analysis of extracts on HepG2 cells, using Phospho-WASP (Tyr290) Rabbit Polyclonal Antibody (EAB14097) at 1:1000 dilution. The lane on the left is blocked with the phospho peptide.
Predicted band size: 53 kDa; Observed band size: 60 kDa |
