www.ebiocell.com
| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 39 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 | |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Wnt3a Rabbit Polyclonal Antibody detects endogenous levels of Wnt3a protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Wnt3a plays a crucial role in intercellular signaling, particularly in mediating cytoskeletal reorganization and regulating the development of the hippocampus, which is essential for cognitive functions such as learning and memory. The importance of Wnt3a′s function is underscored by involvement in oncogenesis and developmental processes, as Wnt3a influences cell fate and patterning during embryogenesis. Notably, Wnt3a is highly conserved across species, with human Wnt3a exhibiting 96% homology to mouse Wnt3a and 84% homology to human Wnt3, indicating a fundamental role in biological systems. The human Wnt3a gene is located at chromosome 1q42, where Wnt3a clusters with the Wnt14 gene, further emphasizing significance in the Wnt signaling pathway. |
| Product Image Gallery | |
 Western blot analysis of extracts on MCF7, Mouse skin, Rat skin cells, using Wnt3a Rabbit Polyclonal Antibody (EAB14102) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
|
