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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF, ELISA | 32 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 IF=1:50-300 |
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| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | XRCC2 Rabbit Polyclonal Antibody detects endogenous levels of XRCC2 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
XRCC2 is a member of the RecA/Rad51-related protein family. XRCC2 plays a crucial role in maintaining genomic stability by participating in the repair of DNA double-strand breaks via homologous recombination, a vital process for accurate DNA repair during cell division. XRCC2 is primarily located in the nucleus, where XRCC2 interacts with other key proteins involved in the DNA repair machinery, such as Rad51, to facilitate the repair process. XRCC2′s nuclear localization ensures repair mechanisms are efficiently executed at the site of damage, thereby preventing genomic instability that could lead to various diseases, including cancer. Deficiencies in XRCC2 can result in increased sensitivity to DNA-damaging agents and contribute to the development of disorders associated with defective DNA repair. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, HEK293 cells, using XRCC2 Rabbit Polyclonal Antibody (EAB14107) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
 Immunohistochemistry analysis of paraffin-embedded Human lung carcinoma tissue, using XRCC2 Rabbit Polyclonal Antibody (EAB14107) at 1:100 dilution.
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