GLP1R Rabbit Polyclonal Antibody
Catalog #:EAB14124
Host / Isotype Clonality Applications MW (kDa) Reactivity
Rabbit IgG Polyclonal WB, IHC-P, IF, ELISA 53 Human, Mouse, Rat
Applications Dilutions
The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user.
WB=1:500-2000  
IHC-P=1:50-300 
IF=1:50-300
Application Key

WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry

Reactivity Key

H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected

Product Information
Conjugate Unconjugate
Specificity GLP1R Rabbit Polyclonal Antibody detects endogenous levels of GLP1R protein.
Purification Affinity purification
Concentration 1mg/ml
Format Liquid
Formulation In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping Gel Pack
Storage Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
UniProt ID

P43220

Entrez Gene ID

2740

Product Description

GLP1R(Glucagon like peptide 1 receptor) is a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. GLP1R protein plays a crucial role in glucose metabolism and appetite regulation, as GLP1R is primarily located in the hypothalamus, a brain region that governs feeding behavior. This localization is significant because GLP1R mediates the effects of glucagon-like peptide-1 (GLP-1), which not only enhances insulin secretion but also suppresses appetite, making GLP1R a vital target for diabetes and obesity therapies. The interaction between GLP-1 and GLP1R is essential for maintaining glucose homeostasis, and dysregulation of this pathway can lead to metabolic disorders.

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For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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