
| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF, ELISA | 53 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-300 IF=1:50-300 |
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| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | GLP1R Rabbit Polyclonal Antibody detects endogenous levels of GLP1R protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
GLP1R(Glucagon like peptide 1 receptor) is a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. GLP1R protein plays a crucial role in glucose metabolism and appetite regulation, as GLP1R is primarily located in the hypothalamus, a brain region that governs feeding behavior. This localization is significant because GLP1R mediates the effects of glucagon-like peptide-1 (GLP-1), which not only enhances insulin secretion but also suppresses appetite, making GLP1R a vital target for diabetes and obesity therapies. The interaction between GLP-1 and GLP1R is essential for maintaining glucose homeostasis, and dysregulation of this pathway can lead to metabolic disorders. |
| Product Image Gallery | |
![]() Western blot analysis of extracts on Mouse brain, Rat brain cells, using GLP1R Rabbit Polyclonal Antibody (EAB14124) at 1:2000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
![]() Immunohistochemical analysis of paraffin-embedded Human pancreas tissue, using GLP1R Rabbit Polyclonal Antibody (EAB14124) at 1:200 dilution.
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