| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 64 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Acrogranin Rabbit Polyclonal Antibody detects endogenous levels of Acrogranin protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Acrogranin also known as PCDGF, Progranulin, Granulin is a glycosylated protein that plays a crucial role in cell signaling and tumorigenesis. This cysteine-rich protein is primarily located in the extracellular matrix and is secreted by various cell types, including estrogen receptor-positive human breast cancer cells. Acrogranin′s localization facilitates autocrine signaling, promoting cell proliferation and survival, particularly in breast carcinoma. Acrogranin overexpression has been implicated in the progression of human breast cancer, making acrogranin a potential biomarker and therapeutic target. Additionally, acrogranin stimulates the growth of both PC cells and 3T3 fibroblasts, highlighting acrogranin′s importance in tumor biology and tissue remodeling. |
| Product Image Gallery | |
 Western blot analysis of extracts on COS7 cells, using Acrogranin Rabbit Polyclonal Antibody (EAB14135) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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