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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 9 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 | |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | HAMP/Hepcidin Rabbit Polyclonal Antibody detects endogenous levels of HAMP/Hepcidin protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Hepcidin also known as HAMP, HEPC, LEAP1, HFE2B is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. Hepcidin recognizes a protein crucial for maintaining iron balance in the body by controlling iron absorption from the intestine and release from macrophages. Hepcidin achieves this by binding to the iron exporter ferroportin, leading to ferroportin internalization and degradation, which effectively reduces iron levels in circulation. Iron regulation is essential not only for preventing iron overload conditions, such as hemochromatosis, but also for ensuring iron availability for critical biological processes, including hemoglobin synthesis and cellular respiration. |
| Product Image Gallery | |
 Western blot analysis of extracts on MDA-MB-435 cells, using HAMP/Hepcidin Rabbit Polyclonal Antibody (EAB14467) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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